Product Description: BGB-102 is a potent multi-kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9.6 nM, 18 nM and 40.3 nM, respectively.
Applications: Cancer-Kinase/protease
Formula: C22H25BrN4O2
References: [1]Gijsen M, et al. HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. PLoS Biol. 2010 Dec 21;8(12):e1000563.
CAS Number: 807640-87-5
Molecular Weight: 457.36
Compound Purity: 99.52
Research Area: Cancer
Solubility: DMSO : 4.4 mg/mL (ultrasonic)/THF : ≥ 7.27 mg/mL
Target: EGFR