BMP-3, Human

Product Description: BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. BMP-3 Protein, Human is the recombinant human-derived BMP-3 protein, expressed by E. coli , with tag free. The total length of BMP-3 Protein, Human is 110 a.a., with molecular weight of ~12 kDa.

Formula: 651(Gene_ID)P12645 (Q363-R472)(Accession)

Molecular Weight: Approximately 12 kDa

Compound Purity: 98.00

• SKU: MEXHY-P79077-10UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P79077-10UG
• Green Labware: No
• Package Unit: 10 μg
• Quantity Unit: STK