BPR5K230, CAS 3029897-97-7

Product Description: BPR5K230 is a dual inhibitor for the receptor tyrosine kinase MER and AXL, with IC50 of 4.1 nM and 9.2 nM. BPR5K230 inhibits the proliferation of Ba/F3-MER with IC50 of 5 nM. BPR5K230 exhibits good pharmacokinetic characteristics in mice, exhibits anti-inflammatory and antitumor against 4T1, MDA-MB-231, MC38 and Hepa1?6 in mouse models[1].

Formula: C37H30FN7O4

References: [1]Li MC, et al., Discovery of Dual MER/AXL Kinase Inhibitors as Bifunctional Small Molecules for Inhibiting Tumor Growth and Enhancing Tumor Immune Microenvironment. J Med Chem. 2024 Jun 24.

CAS Number: 3029897-97-7

Molecular Weight: 655.68

Research Area: Cancer; Inflammation/Immunology

Target: TAM Receptor

• SKU: MEXHY-162645-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162645-0
• Package Unit: Get quote
• Quantity Unit: STK