BR-cpd7

Product Description: BR-cpd7 is a PROTAC degrader for fibroblast growth factor receptor FGFR1/2 with DC50 of 10 nM. BR-cpd7 arrests cell cycle, inhibits proliferations of FGFR1/2 aberrant activated tumor cells. (Pink: ligand for target protein FGFR-IN-12 (HY-160013); Black: linker; Blue: ligand for E3 ligase Thalidomide-NH-CH2-COOH (HY-131717))[1]

Applications: Cancer-Kinase/protease

Formula: C44H47Cl2N11O8

References: [1]Kong Y, et al., A Selective FGFR1/2 PROTAC Degrader with Antitumor Activity. Mol Cancer Ther. 2024 Jun 10:OF1-OF11.

Molecular Weight: 928.82

Research Area: Cancer

Target: FGFR

• SKU: MEXHY-163705-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163705-10
• Package Unit: 10 mg
• Quantity Unit: STK