BVFP, CAS 357158-20-4

Product Description: BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis[1].

Applications: Neuroscience-Neuromodulation

Formula: C13H8BrF3N2O

References: [1]Lee WC, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.

CAS Number: 357158-20-4

Molecular Weight: 345.11

Compound Purity: 98.12

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Neurotensin Receptor

• SKU: MEXHY-153686-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-153686-10
• Package Unit: 10 mg
• Quantity Unit: STK