Product Description: Candidalysin is a cytolytic peptide toxin, which is initially isolated from Candida albicans and exhibits virulent and avirulent characters. Candidalysin activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) of host cells, activates matrix metalloproteinase (MMP) and calcium flux, resulting in inflammatory responses and recruitment of immune cells. Candidalysin exhibits cytotoxicity by dealing membran damage to host cells[1].
Applications: COVID-19-immunoregulation
Formula: C153H266N38O38S2
References: [1]Naglik JR, et al., Candidalysin: discovery and function in Candida albicans infections. Curr Opin Microbiol. 2019 Dec;52:100-109.
CAS Number: 1906866-53-2
Molecular Weight: 3310.11
Research Area: Infection; Inflammation/Immunology
Target: Calcium Channel;EGFR;MMP
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