Product Description: Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections[1][2][3][4].
Applications: COVID-19-immunoregulation
Formula: C15H16ClN3O5S
References: [1]引用1 ：Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13(1):15529. /[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34(4):547-55. /[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55(6):1473-83. /[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13(4):584-8.
CAS Number: 70356-03-5
Molecular Weight: 385.82
Compound Purity: 99.11
Research Area: Infection; Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 5.83 mg/mL (ultrasonic;warming;heat to 60°C)
Target: 5-HT Receptor;Antibiotic;Bacterial;Penicillin-binding protein (PBP)
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