Cenupatide, CAS 1006388-38-0

Description: Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupatide reverted STZ-induced up-regulation of uPA levels and activity, while uPAR on podocytes and (s)uPAR were unaffected. In glomeruli, Cenupatide inhibited FPR2 expression.

CAS Number: 1006388-38-0

Formula: C28H47N11O5

Molecular Weight: 617,756

References: Dal Monte M, Cammalleri M, Pecci V, Carmosino M, Procino G, Pini A, De Rosa M, Pavone V, Svelto M, Bagnoli P. Inhibiting the urokinase-type plasminogen activator receptor system recovers STZ-induced diabetic nephropathy. J Cell Mol Med. 2018 Nov 13. doi: 10.1111/jcmm.14004. [Epub ahead of print] PubMed PMID: 30426662.

• SKU: TGMTP2338-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TP2338-5mg
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK