CHF-6550

Product Description: CHF-6550 is an antagonist for muscarinic M3 receptor and an agonist for β2 adrenoceptor (MABA), with pKi of 9.3 and 10.6, respectively. CHF-6550 exhibits good hepatocyte clearance in rat models and good pharmacokinetic characteristics in guinea pigs[1].

Applications: COVID-19-immunoregulation

Formula: C42H46N4O8

References: [1]Carzaniga L, et al., Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases. J Med Chem. 2024 Jun 10.

Molecular Weight: 734.84

Research Area: Inflammation/Immunology

Target: Adrenergic Receptor;mAChR

• SKU: MEXHY-163702-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163702-0
• Package Unit: Get quote
• Quantity Unit: STK