Product Description: cis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C23H27Cl2F3N2OS
References: [1]Jennifer M Wenzel, et al. The dopamine antagonist cis-flupenthixol blocks the expression of the conditioned positive but not the negative effects of cocaine in rats. Pharmacol Biochem Behav. 2013 Dec;114-115:90-6./[2]Philip Seeman, et al. Atypical antipsychotics: mechanism of action. Can J Psychiatry. 2002 Feb;47(1):27-38.
CAS Number: 51529-01-2
Molecular Weight: 507.44
Research Area: Neurological Disease
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: 5-HT Receptor;Dopamine Receptor