Cisplatin/Dasatinib prodrug-1

Product Description: Cisplatin/Dasatinib prodrug-1 (Compound 3) is a prodrug of Cisplatin (HY-17394) and Dasatinib (HY-10181). Cisplatin/Dasatinib prodrug-1 exhibits antiproliferative activity against A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1 and HL60 cancer cells with IC50s of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3 and 0.25 μM, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C33H42Cl3N9O6PtS

References: [1]Markova L, et al. Multiaction Pt(IV) Prodrugs Releasing Cisplatin and Dasatinib Are Potent Anticancer and Anti-Invasive Agents Displaying Synergism between the Two Drugs. J Med Chem. 2024 May 31.

Molecular Weight: 994.25

Research Area: Cancer

Target: Src

• SKU: MEXHY-161687-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161687-0
• Package Unit: Get quote
• Quantity Unit: STK