CL-184005, CAS 140466-18-8

Product Description: CL-184005 is an antagonist for platelet-activating factor (PAF), that inhibits the PAF-induced platelet aggregation with IC50 of 600 nM and 510 nM, in human and rabbit platelet-rich plasma. CL-184005 protects the rats from endotoxin-induced gastrointestinal damage and hypotension. CL-184005 exhibits potential attenuating Gram-negative bacterial sepsis[1].

Applications: COVID-19-immunoregulation

Formula: C33H46NO7PS

References: [1]Torley LW, et al., Studies of the effect of a platelet-activating factor antagonist, CL 184,005, in animal models of gram-negative bacterial sepsis. Antimicrob Agents Chemother. 1992 Sep;36(9):1971-7.

CAS Number: 140466-18-8

Molecular Weight: 631.76

Research Area: Infection

Target: Platelet-activating Factor Receptor (PAFR)

• SKU: MEXHY-19126-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19126-0
• Package Unit: Get quote
• Quantity Unit: STK