Cortistatin-8, CAS 485803-62-1

Cortistatin-8, CAS 485803-62-1
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MEXHY-P1139-0
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MedChemExpress

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Product Description: Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C47H68N12O9S2

References: [1]F Prodam, et al. Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans. Neuropeptides. 2008 Feb;42(1):89-93.

CAS Number: 485803-62-1

Molecular Weight: 1009.25

Research Area: Metabolic Disease

Target: GHSR
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SKU MEXHY-P1139-0
Manufacturer MedChemExpress
Manufacturer SKU HY-P1139-0
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