CVRARTR, CAS 2349354-64-7

Product Description: CVRARTR is an antagonist for programmed cell death ligand-1 (PD-L1) with KD of 281 nM. CVRARTR induces the internalization of PD-L1 and downregulates PD-L1 on the cell surface. CVRARTR restores cytokine secretion and T cell proliferation in cell CT26. CVRARTR exhibits antitumor efficacy against in CT26 homograft mouse model[1].

Applications: Cancer-programmed cell death

Formula: C33H64N16O9S

References: [1]Gurung S, et al., Phage display-identified PD-L1-binding peptides reinvigorate T-cell activity and inhibit tumor progression. Biomaterials. 2020 Jul;247:119984.

CAS Number: 2349354-64-7

Molecular Weight: 861.03

Research Area: Cancer

Target: PD-1/PD-L1

• SKU: MEXHY-P10439-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10439-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK