Product Description: CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1].
Applications: Cancer-Kinase/protease
Formula: C24H28N8O
References: [1]Bi Y, et al. A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Genes Dis. 2023 Apr 3;11(1):479-494.
CAS Number: 2644673-04-9
Molecular Weight: 444.53
Research Area: cancer
Solubility: 10 mM in DMSO
Target: FGFR