D3S-001, CAS 2914919-85-8

Product Description: D3S-001 is an orally active inhibitor for KRAS. D3S-001 inhibits the proliferation of KRASG12C mutant H358 and MIA-PA-CA-2 with an IC50 of 0.6 and 0.44 nM. D3S-001 exhibits good metabolic stability in hepatocytes, liver microsomes, plasma and whole blood in various species. D3S-001 exhibits good pharmacokinetic characteristics and antitumor efficacy in mice[1].

Formula: C32H35F6N7O3

References: [1]Xu Y, et al., Crystal form of pyrimidine heterocyclic compound and preparation method therefor. WO2023036282.

CAS Number: 2914919-85-8

Molecular Weight: 679.66

Research Area: Cancer

Target: Ras

• SKU: MEXHY-160023-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160023-0
• Package Unit: Get quote
• Quantity Unit: STK