Dapitant, CAS 153438-49-4

Product Description: Dapitant (RPR 100893) is a non-peptide Substance P antagonist with high affinity for the human NK1 receptor. It belongs to the 7,7,4-trimethylperhydroisoindole class of compounds. Dapitant inhibits the binding of Substance P to NK1 receptors, thereby blocking its neurokinin-mediated effects. This novel antagonist represents a potential therapeutic option for conditions involving Substance P, such as neurogenic inflammation and pain modulation[1].

Applications: COVID-19-immunoregulation

Formula: C37H39NO4

References: [1]SYNTHESIS OF RPR 100893, PROTOTYPE OF A NEW SERIES OF POTENT AND SELECTIVE NON PEPTIDE NKl ANTAGONISTS : THE TRIARYLPERHYDROISOINDOLOLOLS

CAS Number: 153438-49-4

Molecular Weight: 561.71

Research Area: Inflammation/Immunology

Target: Neurokinin Receptor

• SKU: MEXHY-17012-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17012-0
• Package Unit: Get quote
• Quantity Unit: STK