Product Description: Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C6H17Cl2N3S
References: [1]Parsons ME, et, al. Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology. Agents Actions. 1977 Mar; 7(1): 31-7./[2]Paquay JB, et, al. Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. Br J Pharmacol. 1999 May; 127(2): 331-4.
CAS Number: 23256-33-9
Molecular Weight: 234.19
Compound Purity: 99.91
Research Area: Endocrinology
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Histamine Receptor;NO Synthase