DOTA.SA.FAPi (TFA)

Product Description: DOTA.SA.FAPi TFA is a bifunctional DATA5m and DOTA chelator, which is composed of the squaric acid and UAMC1110. DOTA.SA.FAPi TFA inhibits fibroblast activation protein (FAP) with an IC50 of 0.9 nM. DOTA.SA.FAPi TFA targets protease PREP with an IC50 of 5.4 μM. DOTA.SA.FAPi TFA can be used a PET tracer, when labeled with 68Ga, and used for research about cancer[1].

Formula: C45H56F5N11O14

References: [1]Moon ES, et al., Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators. EJNMMI Radiopharm Chem. 2020 Jul 29;5(1):19.

Molecular Weight: 1069.98

Compound Purity: 99.26

Research Area: Cancer

Target: FAP;Prolyl Endopeptidase (PREP)

• SKU: MEXHY-D2363-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-D2363-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK