Edonentan, CAS 210891-04-6

Product Description: Edonentan (BMS 207940) is an antagonist for endothelin receptor (ETA receptor), with a Ki of 10 pM. Edonentan is metabolic stable, exhibits good pharmakokinetic characters in rats. Edonentan regulates the endothelin system, blocks the big Endothelin-induced pressor response in rats model[1].

Applications: Neuroscience-Neuromodulation

Formula: C28H32N4O5S

References: [1]Murugesan N, et al., Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective antagonist. J Med Chem. 2003 Jan 2;46(1):125-37.

CAS Number: 210891-04-6

Molecular Weight: 536.64

Research Area: Cardiovascular Disease

Target: Endothelin Receptor

• SKU: MEXHY-15402-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15402-0
• Package Unit: Get quote
• Quantity Unit: STK