EGFR/DHFR-IN-1

Product Description: EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR with IC50s of 0.151 and 0.541 µM, respectively. EGFR/DHFR-IN-1 arrests the cell cycle at both G0-G1 and S phases[1].

Formula: C24H26N4O5S2

References: [1]Fouad M M, et al. Synthesis and in vitro antitumor evaluation of new thieno [2, 3-d] pyrimidine derivatives as EGFR and DHFR inhibitors[J]. Bioorganic Chemistry, 2024, 148: 107401.

Molecular Weight: 514.62

Research Area: Cancer

Target: Dihydrofolate reductase (DHFR) ;EGFR

• SKU: MEXHY-163722-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163722-0
• Package Unit: Get quote
• Quantity Unit: STK