EGFR-IN-112, CAS 2758436-98-3

Product Description: EGFR-IN-112 (SPP10) is an EGFR kinase inhibitor which exhibits IC50s of 2.31 ± 0.3, 3.16 ± 0.8, and 4.2 ± 0.2 μM, against MCF-7, H69AR, and PC-3 cancer cells, respectively. EGFR-IN-112 also demonstrates selective cytotoxicity against cancer cells[1].

Applications: Cancer-Kinase/protease

Formula: C27H23N3S

References: [1]Harika A, et al. Evaluation of Novel Spiro-pyrrolopyridazine Derivatives as Anticancer Compounds: In Vitro Selective Cytotoxicity, Induction of Apoptosis, EGFR Inhibitory Activity, and Molecular Docking Analysis. ACS Omega Article ASAP

CAS Number: 2758436-98-3

Molecular Weight: 421.56

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-163632-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163632-0
• Package Unit: Get quote
• Quantity Unit: STK