EGFR T790M/L858R-IN-8, CAS 333419-97-9

Product Description: EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, targeting mutant EGFRT790M/L858R with IC50 of 56.8 μM. The anti-proliferative effect of EGFR T790M/L858R-IN-8 on cancer cell lines A549, A431, and NHI-H1975 is not significant[1].

Applications: Cancer-Kinase/protease

Formula: C16H11BrN2O3

References: [1]Bai F, et al. Discovery of novel selective inhibitors for EGFR-T790M/L858R. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1365-70.

CAS Number: 333419-97-9

Molecular Weight: 359.17

Compound Purity: 99.20

Research Area: Cancer

Solubility: DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)

Target: EGFR

• SKU: MEXHY-164056-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164056-10
• Package Unit: 10 mg
• Quantity Unit: STK