EP26

Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma[1].

Formula: C42H42ClFN4O5

References: [1]Yang Z, et al. Discovery of Novel Small-Molecule-Based Potential PD-L1/EGFR Dual Inhibitors with High Druggability for Glioblastoma Immunotherapy. J Med Chem. 2024 May 23;67(10):7995-8019.

Molecular Weight: 737.26

Research Area: Cancer

Target: EGFR;PD-1/PD-L1

• SKU: MEXHY-159101-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-159101-0
• Package Unit: Get quote
• Quantity Unit: STK