Formycin triphosphate, CAS 16409-13-5

Product Description: Formycin triphosphate is a fluorescent analogue of ATP which on binding to enzyme active sites exhibits enhanced fluorescence. Formycin triphosphate is an ATP-competitive chicken liver pyruvate carboxylase inhibitor. Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 at about 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 at about 100 μM[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C10H16N5O13P3

References: [1]P V Attwood, et al. Interaction of formycin A-5'-triphosphate with pyruvate carboxylase. FEBS Lett. 1984 Sep 17;175(1):45-50./[2]C H Chang, et al. Formycin triphosphate as a probe for the ATP binding site involved in the activation of guanylate cyclase. Eur J Pharmacol. 1992 Oct 1;227(2):229-31.

CAS Number: 16409-13-5

Molecular Weight: 507.18

Research Area: Metabolic Disease

Target: Guanylate Cyclase

• SKU: MEXHY-161681-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161681-0
• Package Unit: Get quote
• Quantity Unit: STK