FPT, CAS 2048491-06-9

Product Description: FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT1AR, a full agonist at 5-HT1BR and 5-HT1DR with EC50s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT7R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models[1].

Applications: Neuroscience-Neuromodulation

Formula: C18H20FN

References: [1]Tanishka S Saraf, et al. FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT1A, 5-HT1B, and 5-HT1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Knockout Mice. ACS Chem Neurosci. 2022 Dec 21;13(24):3629-3640.

CAS Number: 2048491-06-9

Molecular Weight: 269.36

Research Area: Neurological Disease

Target: 5-HT Receptor

• SKU: MEXHY-160887-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160887-0
• Package Unit: Get quote
• Quantity Unit: STK