Product Description: FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1]. FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells[2].
Applications: COVID-19-immunoregulation
Formula: C84H140N14O18S.xC2HF3O2
Citations: Food Res Int. 10 October 2022, 112029./J Ethnopharmacol. 2024 Jan 24:117824./Int J Med Sci. 2022 Feb.
References: [1]Cathryn J Kurkjian,et al. The Toll-Like Receptor 2/6 Agonist, FSL-1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome. Sci Rep. 2017 Dec 11;7(1):17355./[2]William A Rose 2nd, et al. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virol J. 2009 Nov 10;6:195.
Molecular Weight: 1666.16 (free acid)
Compound Purity: 99.76
Research Area: Infection
Solubility: H2O : 50 mg/mL (ultrasonic)
Target: Antibiotic;HSV;MMP;Toll-like Receptor (TLR)
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