G7-18NATE (TFA)

Product Description: G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines[1][2].

Formula: C67H80N14O19S.xC2HF3O2

References: [1]Sang J, et al. Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity. Molecules. 2019 Oct 17;24(20):3739./[2]Giricz O, et al. GRB7 is required for triple-negative breast cancer cell invasion and survival. Breast Cancer Res Treat. 2012 Jun;133(2):607-15.

Molecular Weight: 1417.50 (free base)

Compound Purity: 98.59

Research Area: Cancer

Target: Others

• SKU: MEXHY-P10224A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10224A-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK