GLUT1/EGFR-IN-1, CAS 2393787-80-7

Product Description: GLUT1/EGFR-IN-1 (compound H) is a potent inhibitor of GLUT1 and EGFR. GLUT1/EGFR-IN-1 can simultaneously act on the EGFR tyrosine kinase ATP-binding site and inhibit GLUT1-mediated energy metabolism, resulting in reductions in ATP, MMP, intra-cellular lactic acid, and EGFR nuclear transfer. GLUT1/EGFR-IN-1 can be used for nasopharyngeal carcinoma (NPC) and triple-negative breast cancer (TNBC) research[1].

Formula: C44H32N4O5

References: [1]Wang C, et al. Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple-negative breast cancer and nasopharyngeal carcinoma. Eur J Pharm Sci. 2024 Jul 1;198:106789.

CAS Number: 2393787-80-7

Molecular Weight: 696.75

Research Area: Cancer

Target: Apoptosis;EGFR;GLUT

• SKU: MEXHY-163726-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163726-0
• Package Unit: Get quote
• Quantity Unit: STK