hCA/VEGFR-2-IN-5

Product Description: hCA/VEGFR-2 IN-5 (compound 9) is an indolone-phenylsulfonamide and a potential dual inhibitor of cancer-related hCA IX/XII and VEGFR-2. The IC50 values of hCA/VEGFR-2-IN-5 for VEGFR-2, hCA IX and hCA XII are 0.38 μM, 40 and 3.2 nM, respectively. hCA/VEGFR-2-IN-5 has antitumor activity[1].

Applications: Cancer-Kinase/protease

Formula: C26H34N4O10S

References: [1]Abbas HS, et al. New sulfonamide-based glycosides incorporated 1,2,3-triazole as cytotoxic agents through VEGFR-2 and carbonic anhydrase inhibitory activity. Sci Rep. 2024 Jun 6;14(1):13028.

Molecular Weight: 594.63

Research Area: Cancer

Target: Carbonic Anhydrase;VEGFR

• SKU: MEXHY-163710-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163710-0
• Package Unit: Get quote
• Quantity Unit: STK