Product Description: HER2-IN-20 (compound 32) is a potent and selective HER2WT and HER2YVMA inhibitor with IC50 values of 49, 42 nM, respectively. HER2-IN-20 has the potential for the research of non-small cell lung cancer (NSCLC)[1].
Applications: Cancer-Kinase/protease
Formula: C30H27ClFN7O2
References: [1]Hicken EJ, et al. Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA. J Med Chem. 2024 May 31.