HNPMI, CAS 1980848-48-3

HNPMI, CAS 1980848-48-3
SKU
MEXHY-162148-50
Packaging Unit
50 mg
Manufacturer
MedChemExpress

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Product Description: HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].

Applications: Cancer-Kinase/protease

Formula: C22H20N2O3

References: [1]Kandhavelu J, et al. A novel EGFR inhibitor, HNPMI, regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer. Br J Pharmacol. 2024 Jan;181(1):107-124.

CAS Number: 1980848-48-3

Molecular Weight: 360.41

Compound Purity: 99.57

Research Area: cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: EGFR
More Information
SKU MEXHY-162148-50
Manufacturer MedChemExpress
Manufacturer SKU HY-162148-50
Package Unit 50 mg
Quantity Unit STK
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