HNPMI, CAS 1980848-48-3

Product Description: HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].

Applications: Cancer-Kinase/protease

Formula: C22H20N2O3

References: [1]Kandhavelu J, et al. A novel EGFR inhibitor, HNPMI, regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer. Br J Pharmacol. 2024 Jan;181(1):107-124.

CAS Number: 1980848-48-3

Molecular Weight: 360.41

Compound Purity: 99.57

Research Area: cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: EGFR

• SKU: MEXHY-162148-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162148-10
• Package Unit: 10 mg
• Quantity Unit: STK