Product Description: IGF-1R modulator 1 (Example 5) is an IGF-1R modulator, with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB). IGF-1R modulator 1 can be used for research of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors, such as Alzheimer's disease[1].
Formula: C22H17N3O4
References: [1]Gunnar Nordvall, et al. Triazine derivatives for treating diseases relating to neurotrophins. Patent. WO2019162702.
CAS Number: 2375424-89-6
Molecular Weight: 387.39
Research Area: Neurological Disease
Target: EGFR;IGF-1R;Trk Receptor