Product Description: IMMH001, also called SYL930, is an orally active, potent and selective S1P1 (sphingosine-1-phosphate receptor 1) agonist. IMMH001 decreased levels of both chemokines and proinflammatory cytokines, including IL-1β, IL-5, IL-18, IP10, CCL3, and CCL5. IMMH001 can be used for rheumatoid arthritis (RA) research[1][2].
Applications: COVID-19-immunoregulation
Formula: C23H28N2O3
References: [1]Xiao Q, et al. Design and synthesis of analogues of the sphingosine-1-phosphate receptor 1 agonist IMMH001 with improved phosphorylation rate in human blood. Bioorg Med Chem. 2020 Nov 1;28(21):115722./[2]Jin J, et al. Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis. Front Pharmacol. 2019 Sep 19;10:1085.
CAS Number: 1418093-75-0
Molecular Weight: 380.48
Compound Purity: 98.04
Research Area: Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: LPL Receptor
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