JAK-IN-30, CAS 2891469-99-9

Product Description: JAK-IN-30 (compound 31) is a water-soluble JAK inhibitor with IC50 values of 2, 15, 18 and 2 nM for JAK2, JAK1, JAK3 and TYK2, respectively. JAK-IN-30 has research potential for dry eye disease (DED)[1].

Applications: COVID-19-immunoregulation

Formula: C19H26N8S

References: [1]Gordhan HM, et al. Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility. J Med Chem. 2023 Jul 13;66(13):8929-8950.

CAS Number: 2891469-99-9

Molecular Weight: 398.53

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: JAK

• SKU: MEXHY-154994-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-154994-5
• Package Unit: 5 mg
• Quantity Unit: STK