Product Description: JAK-IN-37 (Compound WU4) is a JAK inhibitor, with IC50 values of 0.52, 2.26, 84 and 1.09 nM for JAK1, JAK2, JAK3 and JAK4, respectively. JAK-IN-37 can be used for the research of allogeneic hematopoietic cell transplantation (allo-HCT)[1].
Applications: COVID-19-immunoregulation
Formula: C20H23N7O2S
References: [1]Kim S, et al. Novel JAK Inhibitors to Reduce Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation in a Preclinical Mouse Model. Molecules. 2024 Apr 16;29(8):1801.
Molecular Weight: 425.51
Research Area: Inflammation/Immunology
Target: JAK