Product Description: JNJ-18038683 free base is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.
Applications: Neuroscience-Neuromodulation
Formula: C20H20ClN3
References: [1]Bonaventure P, et al. Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder. J Pharmacol Exp Ther. 2012 Aug;342(2):429-40.
CAS Number: 851373-91-6
Molecular Weight: 337.85
Research Area: Neurological Disease
Target: 5-HT Receptor