KIN-8194, CAS 330786-01-1

Product Description: KIN-8194 is an orally active dual inhibitor of HCK and BTK, with IC50 values of 0.915 and [1][2].

Applications: Cancer-Kinase/protease

Formula: C28H33N7O

References: [1]Lantermans HC, et al. The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma. Leukemia. 2024 Mar 7. /[2]Yang G, et al. The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. Blood. 2021 Nov 18;138(20):1966-1979.

CAS Number: 330786-01-1

Molecular Weight: 483.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Btk;Src

• SKU: MEXHY-15805-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15805-5
• Package Unit: 5 mg
• Quantity Unit: STK