Klotho-derived peptide 1

Product Description: Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model[1].

Applications: COVID-19-immunoregulation

Formula: C149H203N39O43

References: [1]Yuan Q, et al., A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling. Nat Commun. 2022 Jan 21;13(1):438.

Molecular Weight: 3228.44

Research Area: Inflammation/Immunology

Target: p38 MAPK;TGF-beta/Smad

• SKU: MEXHY-P10414-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10414-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK