KOR agonist 2

Product Description: KOR agonist 2 (Compound 23p) is an agonist for κ opioid receptor (KOR) with Ki of 1.9 nM. KOR agonist 2 exhibits analgesic effect in mouse models with ED50 of 1.30 mg/kg. KOR agonist 2 exhibits high clearance rate (2 mg/kg, i.v.) in mice, high metabolism and clearance in liver microsomes[1].

Applications: Neuroscience-Neuromodulation

Formula: C29H35ClN2O4S

References: [1]Gao Y, et al., Discovery of N'-benzyl-3-chloro-N-((1S,3R,4R)-3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)cyclohexyl)benzenesulfonamide as a novel selective KOR ligand. Eur J Med Chem. 2024 Jul 3;276:116643.

Molecular Weight: 543.12

Research Area: Neurological Disease

Target: Opioid Receptor

• SKU: MEXHY-159088-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-159088-0
• Package Unit: Get quote
• Quantity Unit: STK