Product Description: M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs). M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis[1].
Applications: Cancer-programmed cell death
Formula: C86H107N19O20S
References: [1]Xiao H, et al. M2-like tumor-associated macrophage-targeted codelivery of STAT6 inhibitor and IKKβ siRNA induces M2-to-M1 repolarization for cancer immunotherapy with low immune side effects[J]. ACS central science, 2020, 6(7): 1208-1222.
Molecular Weight: 1758.95
Research Area: Cancer
Target: Others
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