Product Description: MBX-2982 is a selective, orally-available G protein-coupled receptor 119 (GPR119) agonist.
Applications: Metabolism-sugar/lipid metabolism
Formula: C22H24N8OS
References: [1]Hothersall JD, et al. Sustained wash-resistant receptor activation responses of GPR119 agonists. Eur J Pharmacol. 2015 Sep 5;762:430-42./[2]Lan H, et al. Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways. Br J Pharmacol. 2012 Apr;165(8):2799-807./[3]Yang JW, et al. GPR119: a promising target for nonalcoholic fatty liver disease. FASEB J. 2016 Jan;30(1):324-35.
CAS Number: 1037792-44-1
Molecular Weight: 448.54
Compound Purity: 98.51
Research Area: Metabolic Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: GPR119