Product Description: Mequitazine (Standard) is the analytical standard of Mequitazine. This product is intended for research and analytical applications. Mequitazine is a potent, and long-acting histamine H1 antagonist.
Formula: C20H22N2S
References: [1]Gonnot V, et al. Expedient synthesis of mequitazine an antihistaminic drug by palladium catalyzed allylic alkylation of sodium phenothiazinate. Chem Pharm Bull (Tokyo). 2009 Nov;57(11):1300-2./[2]El-Nakeeb MA, et a. In vitro antibacterial activity of some antihistaminics belonging to different groups against multi-drug resistant clinical isolates. Braz J Microbiol. 2011 Jul;42(3):980-91./[3]Martinez-Mir I, et al. Antihistaminic and anticholinergic activities of mequitazine in comparison with clemizole. J Pharm Pharmacol. 1988 Sep;40(9):655-6./[4]Satake N, et al. Possible mechanisms of vasoinhibitory effects of mequitazine, an antiallergic agent, on the contractions of isolated rat aorta induced by K+, phenylephrine, 5-hydroxytryptamine, and Ca2+. J Cardiovasc Pharmacol. 1994 Apr;23(4):669-73.
CAS Number: 29216-28-2
Molecular Weight: 322.47
Research Area: Inflammation/Immunology; Endocrinology
Target: Histamine Receptor
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