Product Description: MeSeI exhibits a weak inhibitory activity against monoamine oxidase MAO-A and MAO-B (IC50=198.8 µM). MeSeI regulates dopamine receptor D2 and norepinephrine receptor α2, β1, and exhibits antidepressant-like effect in mice. MeSeI is orally active[1].
Formula: C21H17NSe
References: [1]da Rocha MJ, et al., 1-(Phenylselanyl)-2-(p-tolyl)indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and noradrenergic systems. Brain Res. 2024 Jul 1;1834:148904.
CAS Number: 2901664-87-5
Molecular Weight: 362.33
Research Area: Neurological Disease
Target: Androgen Receptor;Dopamine Receptor;Monoamine Oxidase