Mosapride (citrate dihydrate), CAS 636582-62-2

Product Description: Mosapride (TAK-370) citrate dehydrate is a gastroprokinetic agent with 5-hydroxytryptamine4 receptor agonist activity and has been widely used in the research of a variety of gastrointestinal disorders. Mosapride citrate dihydrate potently inhibits Kv4.3 in a concentration-dependent manner with IC50 values of 15.2 μM[1]. Mosapride citrate dihydrateselectively stimulates upper GI motility in vivo[2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C27H37ClFN3O12

References: [1]Sung KW, et al. Effect of mosapride on Kv4.3 potassium channels expressed in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology. 2013;386(10):905-16./[2]Mine Y, et al. Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro. The Journal of pharmacology and experimental therapeutics. 1997;283(3):1000-8.

CAS Number: 636582-62-2

Molecular Weight: 650.05

Compound Purity: 99.87

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: 5-HT Receptor;Cytochrome P450;Potassium Channel

• SKU: MEXHY-B0189B-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0189B-25
• Package Unit: 25 mg
• Quantity Unit: STK