Product Description: MRS5663 (Compound 3a) is an A3AR agonist, with an EC50 of 5.62 nM for β-arrestin2 recruitment assay. MRS5663 has a cytoprotective effect on skeletal muscle ischemia-reperfusion injury/claudication model[1].
Formula: C22H21ClN6O3
References: [1]Tosh D K, et al. 2-Substituted (N)-Methanocarba A3 Adenosine Receptor Agonists: In Silico, In Vitro, and In Vivo Characterization. ACS Pharmacology & Translational Science, 2024.
CAS Number: 1377272-66-6
Molecular Weight: 452.89
Research Area: Cardiovascular Disease
Target: Adenosine Receptor