MS39, CAS 2675490-92-1

Product Description: MS39 (compound 6) is a potent and selective EGFR degrader. MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells[1].

Applications: Cancer-Kinase/protease

Formula: C55H71ClFN9O7S

References: [1]Cheng M, et al. Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule Degraders. J Med Chem. 2020 Feb 13;63(3):1216-1232.

CAS Number: 2675490-92-1

Molecular Weight: 1056.72

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-157581-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157581-1
• Package Unit: 1 mg
• Quantity Unit: STK