MTX-531, CAS 2791417-66-6

Product Description: MTX-531 is a potent and selective inhibitor of EGFR and PI3K, with IC50s of 14.7 nM and 1.1-233 nM (differ in subtype). MTX-531 can also act as a weak agonist of PPARγ, with the EC50 of 3.4 μM in 293H cells[1].

Formula: C22H20ClN5O2S

References: [1]Christopher E Whitehead, et al. A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nat Cancer. 2024 Jul 11.

CAS Number: 2791417-66-6

Molecular Weight: 453.94

Research Area: Cancer

Target: EGFR;PI3K;PPAR

• SKU: MEXHY-162713-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162713-0
• Package Unit: Get quote
• Quantity Unit: STK