Product Description: N188 is a radioligand based on a bicyclic peptide backbone that targets nectin-4, a protein overexpressed in many tumors. N188 can be efficiently radiolabeled to 68Ga-N188, a radioisotope suitable for positron emission tomography (PET) imaging. The development of N188 and its radiolabeled form 68Ga-N188 can be used for the diagnosis and treatment of tumors such as urothelial carcinoma[1].
Formula: C115H157N27O33S4
References: [1]Duan X, et al. First-in-human study of the radioligand 68Ga-N188 targeting nectin-4 for PET/CT imaging of advanced urothelial carcinoma[J]. Clinical Cancer Research, 2023, 29(17): 3395-3407.
Molecular Weight: 2573.90
Research Area: Cancer
Target: Nectin-4